ISSN 1662-4009 (online)

ey0015.9-9 | Growth, growth hormone and puberty in chronic diseases: novel insights from clinical practice | ESPEYB15

9.9 Growth hormone treatment improves final height and nutritional status of children with chronic kidney disease and growth deceleration

C Bizzarri , A Lonero , M Delvecchio , L Cavallo , MF Faienza , M Giordano , L Dello Strologo , M Cappa

To read the full abstract: J Endocrinol Invest. 2018;41:325-331Growth failure is common in children with chronic kidney disease (CKD) and has a multifactorial etiology. The hypothalamus-pituitary axis is intact, but there is a resistance to growth hormone (GH) action in target tissues, secondary to decreased density of GH receptors, impaired signal transduction and reduced levels of free insu...